The Best Supplements for Constant Fatigue (Backed by Science)

If you’re constantly exhausted, even after a full night’s sleep, you’re not alone.
Fatigue is one of the most common complaints in South Africa today — and often, it’s not just about sleeping more. It’s about healing your body at a cellular level.

If you’re searching for supplements for fatigue South Africa, here’s your science-backed guide to what actually works (and what’s just hype).

Why You’re Always Tired: Root Causes of Fatigue

Fatigue can stem from multiple hidden imbalances:

• Adrenal dysfunction (cortisol issues)
• Mitochondrial damage (energy factory burnout)
• Thyroid dysfunction (low T3 or undiagnosed hypothyroidism)
• Nutrient deficiencies (iron, B12, magnesium)
• Chronic inflammation or gut issues

Simply drinking more coffee won’t fix these. But targeted supplemental support can!

Top Supplements for Fatigue Relief

Here’s what science and clinical practice support:

1. Adrenal Support: Adaptogens

When your stress hormones are out of balance, so is your energy.

Recommended Adaptogens:

• Ashwagandha
• Rhodiola Rosea
• Holy Basil (Tulsi)

✅ Boosts resilience to physical and emotional stress
✅ Balances cortisol naturally

Ask Dr Olz Recommends:
👉 Adreset® by Metagenics (available in South Africa)

2. Energy Nutrients: B Vitamins

You cannot make cellular energy (ATP) without B vitamins.

Key B’s for fatigue:

• B12 (methylcobalamin)
• B6 (P5P form)
• Folate (5-MTHF)

✅ Supports mitochondrial energy
✅ Essential for red blood cell formation

Ask Dr Olz Recommends:
👉 Intrinsi B12 Folate by Metagenics

3. Mitochondria Support: CoQ10 & PQQ

Your mitochondria are the “batteries” of your cells.
Low CoQ10 = low energy.

Supplements:

• CoQ10 (ubiquinol form)
• PQQ (Pyrroloquinoline quinone)

✅ Boosts mitochondrial function
✅ Helps with brain fog and physical stamina

Ask Dr Olz Recommends:
👉 CoQ10 ST-100 by Metagenics

4. Magnesium: The “Relaxation Mineral”

Magnesium deficiency is a huge driver of chronic fatigue, poor sleep, and muscle aches.

✅ Supports over 300 energy reactions
✅ Helps with deep, restorative sleep

Ask Dr Olz Recommends:
👉 Mag Glycinate by Metagenics (gentle on digestion)

5. Iron (if deficient)

Low ferritin levels (even if hemoglobin is normal) can cause:

• Exhaustion
• Brain fog
• Hair loss

✅ Always test iron/ferritin before supplementing.

Ask Dr Olz Recommends:
👉 Hemagenics® by Metagenics (highly absorbable iron)

Extra Boosters

• Omega-3s (EPA/DHA) – reduce inflammation that steals energy
• Vitamin D3 – immune and mitochondrial health
• NAC (N-acetylcysteine) – supports detox and mitochondria

📋 Ask Dr Olz Fatigue Recovery Protocol

When patients in South Africa come to us with fatigue, we use a root-cause approach:

✅ Test for hidden drivers (adrenal, thyroid, gut health)
✅ Tailor supplements based on individual labs
✅ Correct nutrient deficiencies
✅ Support mitochondrial health
✅ Repair stress response and inflammation

💬 Final Thoughts

There’s no one-size-fits-all magic pill.
But by targeting the true root causes with quality supplements, you can finally regain your natural energy and vitality.

Want to create your custom Fatigue Recovery Plan?
👉 Book a consultation with Ask Dr Olz today!

And yes, we ship all science-backed supplements for fatigue across South Africa.